Dr Claire Dewsnap talks about TDF treatments

Dr Claire Dewsnap talks about TDF and what to consider with a TDF containing regimen

DELSTRIGO®▼ (doravirine/3TC/TDF)
Prescribing Information (Great Britain) & Prescribing Information (Northern Ireland) [External links]
PIFELTRO®▼ (doravirine)
Prescribing Information (Great Britain) & Prescribing Information (Northern Ireland) [External links]

Licensed indication

PIFELTRO®▼ (doravirine) 100 mg film-coated tablet is indicated, in combination with other antiretroviral medicinal products, for the treatment of adults, and adolescents aged 12 years and older, weighing at least 35 kg, infected with HIV-1, without past or present evidence of resistance to the NNRTI class.

DELSTRIGO®▼ (100 mg doravirine/300 mg lamivudine/300 mg tenofovir disoproxil fumarate, equivalent to 245 mg tenofovir disoproxil) is indicated for the treatment of adults infected with HIV-1 without past or present evidence of resistance to the NNRTI class, lamivudine or tenofovir.

DELSTRIGO®▼ is also indicated for the treatment of adolescents aged 12 years and older weighing at least 35 kg, who are infected with HIV-1, without the past or present evidence of resistance to the NNRTI class, lamivudine, or tenofovir and who have experienced toxicities which preclude the use of other regimens that do not contain tenofovir disoproxil.

Please consult the SmPC for further information before making any prescribing decisions.

In this video Dr Claire Dewsnap shares a case study of a 55-year old cis female living with HIV, and the evidence that support the use of a TDF-containing regimen.

Please note that this is one individual and cases may vary.

Filming fully organised and funded by MSD, including speaker’s honoraria. Views of the speaker are their own and do not represent the opinions of MSD.

DELSTRIGO has been studied over 4 years in people living with HIV, 12 years and above

Abbreviations

NNRTIs: Non-Nucleoside Reverse Transcriptase Inhibitors; TDF: Tenofovir Disoproxil Fumarate.

Supporting documentation

DELSTRIGO®▼ Prescribing Information (Great Britain) & Prescribing Information (Northern Ireland)
PIFELTRO®▼ Prescribing Information (Great Britain) & Prescribing Information (Northern Ireland)
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