Metabolic Case Study built by your peers

Managing Metabolic Health in Practice: Interactive Case Study by Dr Nasha Matin & Hasan Mirza

DELSTRIGO® (doravirine/lamivudine/tenofovir disoproxil fumarate) Prescribing Information (United Kingdom) [External link]
PIFELTRO® (doravirine) Prescribing Information (United Kingdom) [External link]

The real‑world clinical case study below highlights practical, evidence‑informed approaches to improving metabolic health. Drawing on emerging evidence and evolving treatment options, the case explores common metabolic challenges in people living with HIV (PLWH).

Ms JC: 62-year-old obese woman requiring support with managing her weight

Explore emerging GLP‑1 data in PLWH, implications for ARV selection, and evidence‑based strategies to address statin hesitancy and reduce cardiovascular risk.

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This is based on a real case with details amended for confidentiality purposes. This is an individual case and other cases may vary

PIFELTRO® (doravirine) 100 mg film-coated tablet is indicated, in combination with other antiretroviral medicinal products, for the treatment of adults, and adolescents aged 12 years and older, weighing at least 35 kg, infected with HIV-1, without past or present evidence of resistance to the NNRTI class.

DELSTRIGO® (100 mg doravirine/300 mg lamivudine/300 mg tenofovir disoproxil fumarate, equivalent to 245 mg tenofovir disoproxil) is indicated for the treatment of adults infected with HIV-1 without past or present evidence of resistance to the NNRTI class, lamivudine or tenofovir.

DELSTRIGO® is also indicated for the treatment of adolescents aged 12 years and older weighing at least 35 kg, who are infected with HIV-1, without the past or present evidence of resistance to the NNRTI class, lamivudine, or tenofovir and who have experienced toxicities which preclude the use of other regimens that do not contain tenofovir disoproxil.

Please consult the SmPC for further information before making any prescribing decisions.

Supporting documentation

DELSTRIGO® Prescribing Information (United Kingdom) [External link]
PIFELTRO® Prescribing Information (United Kingdom) [External link]
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